Exposure of Pregnant Rats to Cigarette-Smoke Condensate Causes Glomerular Abnormalities in Offspring
نویسندگان
چکیده
منابع مشابه
Exposure of pregnant rats to cigarette-smoke condensate causes glomerular abnormalities in offspring.
BACKGROUND Higher blood pressure and albuminuria are found in offspring of mothers who smoke during pregnancy. Whether or not kidney development is affected by maternal smoking is unknown. METHODS Sprague-Dawley rats were randomly allocated to twice-daily cigarette smoke and nicotine condensate (1 mg/kg) or vehicle at day 10 of pregnancy until delivery. RESULTS Exposed offspring did not dif...
متن کاملExposure of pregnant women to waterpipe and cigarette smoke.
INTRODUCTION Throughout the Eastern Mediterranean region, tobacco is used primarily in 2 forms: cigarette smoking and waterpipe smoking. Despite the fact that tobacco use is considered as a global public health threat, waterpipe smoking is reported to be growing in popularity, particularly among women. The objectives of this study are to determine the prevalence and patterns of cigarette, water...
متن کاملCigarette smoke exposure causes constriction of rat lung.
Cigarette smoke is known to cause acute increases in airway resistance, but the mechanisms behind this effect are unknown. Lung explants were utilized to examine the constrictive effects of acute cigarette smoke exposure on bronchioles from rats in vitro that had or had not been previously exposed to cigarette smoke in vivo. It was found that smoke induced a small but consistent degree of contr...
متن کاملGestational Zearalenone Exposure Causes Reproductive and Developmental Toxicity in Pregnant Rats and Female Offspring
Zearalenone (ZEN) is an oestrogenic mycotoxin commonly found in food and feed products and can affect reproduction and development in both humans and animals. This study aimed to determine the toxic effects of ZEN on maternal SD rats and the F1 female offspring. Sixty-four pregnant rats were divided into 4 groups and exposed to feed contaminated with ZEN (0, 5, 10, and 20 mg/kg feed) on gestati...
متن کاملSidestream cigarette smoke exposure effects on baroreflex in adult rats.
BACKGROUND It has been evidenced in the literature that exposure to cigarette smoke causes hypertension in rats; however, it has not been demonstrated if the baroreflex function is impaired before the animal becomes hypertensive. OBJECTIVE We evaluated short-term effects of sidestream cigarette smoke (SSCS) exposure on baroreflex function in Wistar normotensive rats. METHODS Rats were expos...
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ژورنال
عنوان ژورنال: Kidney and Blood Pressure Research
سال: 2012
ISSN: 1423-0143,1420-4096
DOI: 10.1159/000341489